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The lead analogue, MT2-4, demonstrated 18-fold selectivity for MC1R over MC4R in HEK293 cells transfected with human receptor constructs

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[DOI] [PMC free article] [PubMed] [Google Scholar] 57.de Graaf C., Donnelly D., Wootten D., Lau J., Sexton P.M., Miller L.J., Ahn J.M., Liao J., Fletcher M.M., Yang D., et al